Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial
Asthma is a chronic inflammatory disease of the airways mediated, at least in part, by leukotrienes and other lipid mediators. Experimental studies have shown that lipid extract of New Zealand green-lipped mussel, Perna canaliculus, is effective in inhibiting 59-lipoxygenase and cyclo-oxygenase pathways responsible for production of eicosanoids, including leukotrienes and prostaglandins.
The Asthma Journal of New Zealand Treatment of Asthma Emelyanov & Barnes
Asthma is a chronic inflammatory disease of the airways mediated at least in part by leukotrienes and other lipid mediators. Experimental studies have shown that lipid extract of New Zealand Green-lipped mussel, Perna canaliculus, is effective in inhibiting 5′- Lipoxygenase and cyclo-oxygenase pathways responsible for production of eicosanoids, including leukotrienes and prostaglandins.
Treatment of Children’s Asthma with a Lipid Extract of the New Zealand Green Lipped Mussel
Oily fish and shellfish are rich in the omega-3 fatty acids eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA). The potential anti-inflammatory effect of fish oil is that these long
chain polyunsaturated fatty acids (PUFAs) competitively inhibit the formation of leukotrienes and
prostaglandins from arachidonic acid this may reduce airway inflammation and
bronchoconstriction.
Marine lipid fraction PCSO-524 of the NewZealand green lipped mussel attenuates hyperpneainduced bronchoconstriction in asthma
Evaluate the effect of the marine lipid fraction of the New Zealand green-lipped mussel (Pernacanaliculus) PCSO-524 (Lyprinol /OmegaXL ), rich in omega-3 fatty acids, on air way in flammation and the bronchoconstrictor response to eucapnic voluntary hyperpnea (EVH) inasthmatics.
Lyprinol Inhibe La Production De Ltb, Par Les Monocytes Humains
The effect of Lyprinol was evaluated on LTB4-induced human monocytes (normal and allergic donors) activation. Peripheral blood normal monocyte-derived monocytes when stimulated by Interleukin-4 (IL-4) produced high amounts of leukotriene B4 (LTB4) through the activation of the 5-lipoxygenase pathway.
Immunomodulating Effect of Lyprinol in Humans Vaccinated with Live Influenza Vaccine
Live cold-adapted reassortant influenza vaccine (LAIV) is an effective
means of controlling influenza among children, adults and elderly [1-3].
In comparison with inactivated influenza vaccines, LAIV has the
advantages of stimulating the mucosal as well as cellular immune responses whereas it is slightly less effective in stimulating the serum antibody responses.